Variation in the 4q25 Chromosomal Locus Predicts Atrial Fibrillation After Coronary Artery Bypass Graft Surgery | Zendy

Simon C. Body | Zendy; Charles D. Collard | Zendy; Stanton K. Shernan | Zendy; Amanda A. Fox | Zendy; Kuang-Yu Liu | Zendy; Marylyn D. Ritchie | Zendy; Tjörvi E. Perry | Zendy; Jochen D. Muehlschlegel | Zendy; Sary F. Aranki | Zendy; Brian S. Donahue | Zendy; Mias Pretorius | Zendy; Juan-Carlos Estrada | Zendy; Patrick T. Ellinor | Zendy; Christopher NewtonCheh | Zendy; Christine E. Seidman | Zendy; Jonathan G. Seidman | Zendy; Daniel S. Herman | Zendy; Peter Lichtner | Zendy; Thomas Meitinger | Zendy; Arne Pfeufer | Zendy; Stefan Kääb | Zendy; Nancy J. Brown | Zendy; Dan M. Roden | Zendy; Dawood Darbar | Zendy

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Variation in the 4q25 Chromosomal Locus Predicts Atrial Fibrillation After Coronary Artery Bypass Graft Surgery

Author(s) -

Simon C. Body,

Charles D. Collard,

Stanton K. Shernan,

Amanda A. Fox,

Kuang-Yu Liu,

Marylyn D. Ritchie,

Tjörvi E. Perry,

Jochen D. Muehlschlegel,

Sary F. Aranki,

Brian S. Donahue,

Mias Pretorius,

Juan-Carlos Estrada,

Patrick T. Ellinor,

Christopher NewtonCheh,

Christine E. Seidman,

Jonathan G. Seidman,

Daniel S. Herman,

Peter Lichtner,

Thomas Meitinger,

Arne Pfeufer,

Stefan Kääb,

Nancy J. Brown,

Dan M. Roden,

Dawood Darbar

Publication year - 2009

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.109.849075

Subject(s) - medicine , single nucleotide polymorphism , cohort , cardiology , atrial fibrillation , coronary artery bypass surgery , genotyping , odds ratio , cardiac surgery , artery , genotype , genetics , biology , gene

Atrial fibrillation (AF) is the most common adverse event following coronary artery bypass graft surgery. A recent study identified chromosome 4q25 variants associated with AF in ambulatory populations. However, their role in postoperative AF is unknown. We hypothesized that genetic variants in the 4q25 chromosomal region are independently associated with postoperative AF after coronary artery bypass graft surgery.

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