The FTO Gene Is Associated With an Atherogenic Lipid Profile and Myocardial Infarction in Patients With Type 2 Diabetes | Zendy

Alex S. F. Doney | Zendy; Jennifer Dannfald | Zendy; Charlotte H. Kimber | Zendy; Louise A. Donnelly | Zendy; Ewan R. Pearson | Zendy; Andrew D. Morris | Zendy; Nicholette D. Palmer | Zendy

Open Access

The FTO Gene Is Associated With an Atherogenic Lipid Profile and Myocardial Infarction in Patients With Type 2 Diabetes

Author(s) -

Alex S. F. Doney,

Jennifer Dannfald,

Charlotte H. Kimber,

Louise A. Donnelly,

Ewan R. Pearson,

Andrew D. Morris,

Nicholette D. Palmer

Publication year - 2009

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.108.822320

Subject(s) - medicine , body mass index , myocardial infarction , hazard ratio , type 2 diabetes , diabetes mellitus , obesity , endocrinology , insulin resistance , genotype , prospective cohort study , cardiology , confidence interval , biology , gene , genetics

Common variation in the fat mass and obesity (FTO)-related gene is associated with increased body fat and susceptibility to type 2 diabetes. We hypothesized that this would also associate with metabolic phenotypes of insulin resistance and increased risk of cardiovascular morbidity and mortality.

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