Altered Hepatic Gene Expression Profiles Associated With Myocardial Ischemia | Zendy

Hiroshi Ootsuji | Zendy; Masao Honda | Zendy; Shuichi Kaneko | Zendy; Soichiro Usui | Zendy; Masaki Okajima | Zendy; Hikari Okada | Zendy; Yoshio Sakai | Zendy; Toshinari Takamura | Zendy; Katsuhisa Horimoto | Zendy; Masayuki Takamura | Zendy

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Altered Hepatic Gene Expression Profiles Associated With Myocardial Ischemia

Author(s) -

Hiroshi Ootsuji,

Masao Honda,

Shuichi Kaneko,

Soichiro Usui,

Masaki Okajima,

Hikari Okada,

Yoshio Sakai,

Toshinari Takamura,

Katsuhisa Horimoto,

Masayuki Takamura

Publication year - 2009

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.108.795484

Subject(s) - ischemia , osteopontin , medicine , pathophysiology , myocardial infarction , cardiology , endocrinology

Acute coronary syndrome is sometimes accompanied by accelerated coagulability, lipid metabolism, and inflammatory responses, which are not attributable to the cardiac events alone. We hypothesized that the liver plays a pivotal role in the pathophysiology of acute coronary syndrome. We simultaneously analyzed the gene expression profiles of the liver and heart during acute myocardial ischemia in mice.

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