Common Variants in Cardiac Ion Channel Genes Are Associated With Sudden Cardiac Death
Author(s) -
Christine M. Albert,
Calum A. MacRae,
Daniel I. Chasman,
Martin VanDenburgh,
Julie E. Buring,
JoAnn E. Manson,
Nancy R. Cook,
Christopher NewtonCheh
Publication year - 2010
Publication title -
circulation arrhythmia and electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.684
H-Index - 102
eISSN - 1941-3149
pISSN - 1941-3084
DOI - 10.1161/circep.110.944934
Subject(s) - sudden cardiac death , odds ratio , single nucleotide polymorphism , sudden death , medicine , qt interval , population , minor allele frequency , cardiology , biology , genetics , genotype , gene , environmental health
Rare variants in cardiac ion channel genes are associated with sudden cardiac death in rare primary arrhythmic syndromes; however, it is unknown whether common variation in these same genes may contribute to sudden cardiac death risk at the population level.
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