Atherosclerosis Immunoimaging by Positron Emission Tomography | Zendy

Carlos PérezMedina | Zendy; Zahi A. Fayad | Zendy; Willem J. M. Mulder | Zendy

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Atherosclerosis Immunoimaging by Positron Emission Tomography

Author(s) -

Carlos PérezMedina,

Zahi A. Fayad,

Willem J. M. Mulder

Publication year - 2020

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.119.313455

Subject(s) - positron emission tomography , tomography , brain positron emission tomography , medicine , nuclear medicine , preclinical imaging , radiology , biology , in vivo , microbiology and biotechnology

The immune system’s role in atherosclerosis has long been an important research topic and is increasingly investigated for therapeutic and diagnostic purposes. Therefore, noninvasive imaging of hematopoietic organs and immune cells will undoubtedly improve atherosclerosis phenotyping and serve as a monitoring method for immunotherapeutic treatments. Among the available imaging techniques, positron emission tomography’s unique features make it an ideal tool to quantitatively image the immune response in the context of atherosclerosis and afford reliable readouts to guide medical interventions in cardiovascular disease. Here, we summarize the state of the art in the field of atherosclerosis positron emission tomography immunoimaging and provide an outlook on current and future applications.

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