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Vascular Semaphorin 7A Upregulation by Disturbed Flow Promotes Atherosclerosis Through Endothelial β1 Integrin
Author(s) -
Shuhong Hu,
Yifei Liu,
Tao You,
Jack Heath,
Linru Xu,
Xiaowei Zheng,
Aili Wang,
Yinyan Wang,
Fengchan Li,
Fei Yang,
Yiren Cao,
Huayu Zhang,
Janine M. van Gils,
Anton Jan van Zonneveld,
Hanjoong Jo,
Qingyu Wu,
Yonghong Zhang,
Chaojun Tang,
Li Zhu
Publication year - 2017
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.117.310491
Subject(s) - downregulation and upregulation , semaphorin , integrin , microbiology and biotechnology , endothelium , biology , medicine , receptor , gene , biochemistry
Accumulating evidence suggests a role of semaphorins in vascular homeostasis. Here, we investigate the role of Sema7A (semaphorin 7A) in atherosclerosis and its underlying mechanism.

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