Multidisciplinary Approach to Understand Medial Arterial Calcification | Zendy

Ophélie Gourgas | Zendy; Juliana Marulanda | Zendy; Peng Zhang | Zendy; Monzur Murshed | Zendy; Marta Cerruti | Zendy

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Multidisciplinary Approach to Understand Medial Arterial Calcification

Author(s) -

Ophélie Gourgas,

Juliana Marulanda,

Peng Zhang,

Monzur Murshed,

Marta Cerruti

Publication year - 2017

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.117.309808

Subject(s) - calcification , medicine , multidisciplinary approach , cardiology , sociology , social science

Vascular calcification significantly increases morbidity in life-threatening diseases, and no treatments are available because of lack of understanding of the underlying molecular mechanism. Here, we study the physicochemical details of mineral nucleation and growth in an animal model that faithfully recapitulates medial arterial calcification in humans, to understand how pathological calcification is initiated on the vascular extracellular matrix.

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