Impact of CD14 Polymorphisms on Anti-Apolipoprotein A-1 IgG-Related Coronary Artery Disease Prediction in the General Population | Zendy

Panagiotis Antiochos | Zendy; Pedro MarquesVidal | Zendy; Julien Virzi | Zendy; Sabrina Pagano | Zendy; Nathalie Satta | Zendy; Oliver Hartley | Zendy; Fabrizio Montecucco | Zendy; François Mach | Zendy; Zoltán Kutalik | Zendy; Gérard Waeber | Zendy; Péter Vollenweider | Zendy; Nicolas Vuilleumier | Zendy

Open Access

Impact of CD14 Polymorphisms on Anti-Apolipoprotein A-1 IgG-Related Coronary Artery Disease Prediction in the General Population

Author(s) -

Panagiotis Antiochos,

Pedro MarquesVidal,

Julien Virzi,

Sabrina Pagano,

Nathalie Satta,

Oliver Hartley,

Fabrizio Montecucco,

François Mach,

Zoltán Kutalik,

Gérard Waeber,

Péter Vollenweider,

Nicolas Vuilleumier

Publication year - 2017

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.117.309602

Subject(s) - apolipoprotein b , coronary artery disease , medicine , disease , population , cholesterol , environmental health

We aimed to determine whether autoantibodies against apoA-1 (apolipoprotein A-1; anti-apoA-1 IgG) predict incident coronary artery disease (CAD), defined as adjudicated incident myocardial infarction, angina, percutaneous coronary revascularization, or bypass grafting, in the general population. We further investigated whether this association is modulated by a functional CD14 receptor single nucleotide polymorphism.

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