Apolipoprotein A-I Mimetic Peptides | Zendy

Michael Ditiatkovski | Zendy; Jonatan Palsson | Zendy; Jaye ChinDusting | Zendy; Alan T. Remaley | Zendy; Dmitri Sviridov | Zendy

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Apolipoprotein A-I Mimetic Peptides

Author(s) -

Michael Ditiatkovski,

Jonatan Palsson,

Jaye ChinDusting,

Alan T. Remaley,

Dmitri Sviridov

Publication year - 2017

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.117.309523

Subject(s) - in vivo , apolipoprotein b , in vitro , cholesterol , chemistry , lipoprotein , biochemistry , peptide , efflux , pharmacology , biology , microbiology and biotechnology

Apolipoprotein A-I (apoA-I) mimetic peptides have antiatherogenic properties of high-density lipoprotein in vitro and have been shown to inhibit atherosclerosis in vivo. It is unclear, however, if each in vitro antiatherogenic property of these peptides translates to a corresponding activity in vivo, and if so, which of these contributes most to reduce atherosclerosis.

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