Endothelial Cell Autophagy Maintains Shear Stress–Induced Nitric Oxide Generation via Glycolysis-Dependent Purinergic Signaling to Endothelial Nitric Oxide Synthase | Zendy

Leena P. Bharath | Zendy; Jae Min Cho | Zendy; Seul-Ki Park | Zendy; Ting Ruan | Zendy; Youyou Li | Zendy; Robert A. Mueller | Zendy; Tyler Bean | Zendy; Van Reese | Zendy; R. S. Richardson | Zendy; Jinjin Cai | Zendy; Ashot Sargsyan | Zendy; Karla Maria Pereira Pires | Zendy; Pon Velayutham Anandh Babu | Zendy; Sihem Boudina | Zendy; Timothy E. Graham | Zendy; J. David Symons | Zendy

Open Access

Endothelial Cell Autophagy Maintains Shear Stress–Induced Nitric Oxide Generation via Glycolysis-Dependent Purinergic Signaling to Endothelial Nitric Oxide Synthase

Author(s) -

Leena P. Bharath,

Jae Min Cho,

Seul-Ki Park,

Ting Ruan,

Youyou Li,

Robert A. Mueller,

Tyler Bean,

Van Reese,

R. S. Richardson,

Jinjin Cai,

Ashot Sargsyan,

Karla Maria Pereira Pires,

Pon Velayutham Anandh Babu,

Sihem Boudina,

Timothy E. Graham,

J. David Symons

Publication year - 2017

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.117.309510

Subject(s) - purinergic receptor , microbiology and biotechnology , small interfering rna , p2y receptor , nitric oxide synthase type iii , autophagy , purinergic signalling , chemistry , nitric oxide synthase , nitric oxide , protein kinase c , biology , signal transduction , enos , biochemistry , receptor , endocrinology , adenosine receptor , transfection , apoptosis , gene , agonist , extracellular

Impaired endothelial cell (EC) autophagy compromises shear stress-induced nitric oxide (NO) generation. We determined the responsible mechanism.

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