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Estimating the Population Impact of Lp(a) Lowering on the Incidence of Myocardial Infarction and Aortic Stenosis—Brief Report
Author(s) -
Mehdi Afshar,
Pia R. Kamstrup,
Ken Williams,
Allan D. Sniderman,
Børge G. Nordestgaard,
George Thanassoulis
Publication year - 2016
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.116.308271
Subject(s) - attributable risk , medicine , population , relative risk , risk factor , lipoprotein(a) , myocardial infarction , confidence interval , absolute risk reduction , dyslipidemia , cardiology , epidemiology , lipoprotein , cholesterol , obesity , environmental health
High lipoprotein(a) (Lp[a]) is the most common genetic dyslipidemia and is a causal factor for myocardial infarction (MI) and aortic stenosis (AS). We sought to estimate the population impact of Lp(a) lowering that could be achieved in primary prevention using the therapies in development.

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