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Cardiac and Carotid Markers Link With Accelerated Brain Atrophy
Author(s) -
Behnam Sabayan,
Mark A. van Buchem,
Sigurður Sigurðsson,
Qian Zhang,
Osorio Meirelles,
Tamara B. Harris,
Vilmundur Guðnason,
Andrew E. Arai,
Lenore J. Launer
Publication year - 2016
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.116.308018
Subject(s) - medicine , cardiology , magnetic resonance imaging , atrophy , brain natriuretic peptide , white matter , natriuretic peptide , confidence interval , population , cardiac magnetic resonance imaging , intima media thickness , brain size , heart failure , radiology , carotid arteries , environmental health
Pathologies in the heart-brain axis might, independently or in combination, accelerate the process of brain parenchymal loss. We aimed to investigate the association of serum N-terminal brain natriuretic peptide (NT-proBNP), as a marker of cardiac dysfunction, and carotid intima media thickness (CIMT), as a marker of carotid atherosclerosis burden, with structural brain changes.

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