MYOSLID Is a Novel Serum Response Factor–Dependent Long Noncoding RNA That Amplifies the Vascular Smooth Muscle Differentiation Program | Zendy

Jinjing Zhao | Zendy; Wei Zhang | Zendy; Mingyan Lin | Zendy; Wen Wu | Zendy; Pengtao Jiang | Zendy; Emiley Tou | Zendy; Min Xue | Zendy; Angelene F. Richards | Zendy; David Jourd’heuil | Zendy; Arif Asif | Zendy; Deyou Zheng | Zendy; Harold A. Singer | Zendy; Joseph M. Miano | Zendy; Xiaochun Long | Zendy

Open Access

MYOSLID Is a Novel Serum Response Factor–Dependent Long Noncoding RNA That Amplifies the Vascular Smooth Muscle Differentiation Program

Author(s) -

Jinjing Zhao,

Wei Zhang,

Mingyan Lin,

Wen Wu,

Pengtao Jiang,

Emiley Tou,

Min Xue,

Angelene F. Richards,

David Jourd’heuil,

Arif Asif,

Deyou Zheng,

Harold A. Singer,

Joseph M. Miano,

Xiaochun Long

Publication year - 2016

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.116.307879

Subject(s) - myocardin , serum response factor , vascular smooth muscle , smad , transforming growth factor , transcription factor , biology , microbiology and biotechnology , long non coding rna , growth factor , signal transduction , gene expression , cancer research , medicine , endocrinology , gene , rna , genetics , smooth muscle , receptor

Long noncoding RNAs (lncRNA) represent a growing class of noncoding genes with diverse cellular functions. We previously reported on SENCR, an lncRNA that seems to support the vascular smooth muscle cell (VSMC) contractile phenotype. However, information about the VSMC-specific lncRNAs regulated by myocardin (MYOCD)/serum response factor, the master switch for VSMC differentiation, is unknown.

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