Open AccessVitamin K–Dependent Protein Activity and Incident Ischemic Cardiovascular Disease
Author(s) -
John Danziger,
Rebekah Young,
M. Kyla Shea,
Russell P. Tracy,
Joachim H. Ix,
Nancy S. Jenny,
Kenneth J. Mukamal
Publication year - 2016
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.116.307273
Subject(s) - medicine , disease , cardiology , vitamin d and neurology , vitamin
Vitamin K-dependent proteins (VKDPs), which require post-translational modification to achieve biological activity, seem to contribute to thrombus formation, vascular calcification, and vessel stiffness. Whether VKDP activity is prospectively associated with incident cardiovascular disease has not been studied.
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