Modulation of Kinin B2 Receptor Signaling Controls Aortic Dilatation and Rupture in the Angiotensin II–Infused Apolipoprotein E–Deficient Mouse | Zendy

Corey S. Moran | Zendy; C. M. Rush | Zendy; Tammy Dougan | Zendy; Roby J. Jose | Zendy; Erik Biroš | Zendy; Paul E. Norman | Zendy; Lajos Gera | Zendy; Jonathan Golledge | Zendy

Open Access

Modulation of Kinin B2 Receptor Signaling Controls Aortic Dilatation and Rupture in the Angiotensin II–Infused Apolipoprotein E–Deficient Mouse

Author(s) -

Corey S. Moran,

C. M. Rush,

Tammy Dougan,

Roby J. Jose,

Erik Biroš,

Paul E. Norman,

Lajos Gera,

Jonathan Golledge

Publication year - 2016

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.306945

Subject(s) - angiotensin ii , kinin , agonist , endocrinology , medicine , receptor antagonist , antagonist , receptor , pharmacology , bradykinin

Abdominal aortic aneurysm (AAA) is an important cause of mortality in older adults. Activity of the local kallikrein-kinin system may be important in cardiovascular disease. The effect of kinin B2 receptor (B2R) agonist and antagonist peptides on experimental AAA was investigated.

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