Association Between Family History, a Genetic Risk Score, and Severity of Coronary Artery Disease in Patients With Premature Acute Coronary Syndromes | Zendy

Waseem Hindieh | Zendy; Louise Pilote | Zendy; Asim N. Cheema | Zendy; Hatim Al-Lawati | Zendy; Christopher Labos | Zendy; Line Dufresne | Zendy; James C. Engert | Zendy; George Thanassoulis | Zendy

Open Access

Association Between Family History, a Genetic Risk Score, and Severity of Coronary Artery Disease in Patients With Premature Acute Coronary Syndromes

Author(s) -

Waseem Hindieh,

Louise Pilote,

Asim N. Cheema,

Hatim Al-Lawati,

Christopher Labos,

Line Dufresne,

James C. Engert,

George Thanassoulis

Publication year - 2016

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.306944

Subject(s) - medicine , coronary artery disease , cardiology , family history , framingham risk score , disease , association (psychology) , psychology , psychotherapist

A genetic risk score (GRS) for coronary artery disease has recently been shown to be independent of family history (FHx) in predicting future cardiovascular events. We sought to determine whether the presence of these risk factors, either individually or together, was associated with a higher burden of angiographic coronary artery disease.

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