Low Levels of Apolipoprotein B-100 Autoantibodies Are Associated With Increased Risk of Coronary Events | Zendy

Harry Björkbacka | Zendy; Ragnar Alm | Zendy; Margaretha Persson | Zendy; Bo Hedblad | Zendy; Jan Nilsson | Zendy; Gunilla Nordin Fredrikson | Zendy

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Low Levels of Apolipoprotein B-100 Autoantibodies Are Associated With Increased Risk of Coronary Events

Author(s) -

Harry Björkbacka,

Ragnar Alm,

Margaretha Persson,

Bo Hedblad,

Jan Nilsson,

Gunilla Nordin Fredrikson

Publication year - 2016

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.306938

Subject(s) - hazard ratio , medicine , confidence interval , apolipoprotein b , autoantibody , odds ratio , prospective cohort study , proportional hazards model , gastroenterology , population , endocrinology , immunology , cholesterol , antibody , environmental health

Previous smaller studies have indicated inverse associations between autoantibodies to oxidized low-density lipoprotein epitopes, and cardiovascular disease. The present study investigated associations between autoantibodies against the apolipoprotein B-100 peptides p45 and p210, respectively, and risk of incident cardiovascular disease in a large population-based cohort.

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