Extended-Release Niacin/Laropiprant Improves Overall Efficacy of Postprandial Reverse Cholesterol Transport | Zendy

Petra El Khoury | Zendy; Elisa Waldmann | Zendy; Thierry Huby | Zendy; Julie Gall | Zendy; Philippe Couvert | Zendy; JeanMarc Lacorte | Zendy; John Chapman | Zendy; Éric Frisdal | Zendy; Philippe Lesnik | Zendy; Klaus G. Parhofer | Zendy; Wilfried Le Goff | Zendy; Maryse Guérin | Zendy

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Extended-Release Niacin/Laropiprant Improves Overall Efficacy of Postprandial Reverse Cholesterol Transport

Author(s) -

Petra El Khoury,

Elisa Waldmann,

Thierry Huby,

Julie Gall,

Philippe Couvert,

JeanMarc Lacorte,

John Chapman,

Éric Frisdal,

Philippe Lesnik,

Klaus G. Parhofer,

Wilfried Le Goff,

Maryse Guérin

Publication year - 2015

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.306834

Subject(s) - postprandial , cholesterylester transfer protein , hypertriglyceridemia , medicine , niacin , reverse cholesterol transport , endocrinology , cholesterol , lipoprotein , chemistry , apolipoprotein b , triglyceride , pharmacology , insulin

Postprandial atherogenic lipoproteins, characterizing high-risk patients, correlate positively with cardiovascular events. Although the effect of niacin on fasting lipids is well established, its impact on atheroprotective reverse cholesterol transport (RCT) pathway and on functional features of circulating lipoproteins during the postprandial state remains indeterminate.

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