Glycosphingolipids on Human Myeloid Cells Stabilize E-Selectin–Dependent Rolling in the Multistep Leukocyte Adhesion Cascade | Zendy

Nandini Mondal | Zendy; Gino Stolfa | Zendy; Aristotelis Antonopoulos | Zendy; Yuqi Zhu | Zendy; Shuen-Shiuan Wang | Zendy; Alexander Buffone | Zendy; G. Ekin AtillaGokcumen | Zendy; Stuart M. Haslam | Zendy; Anne Dell | Zendy; Sriram Neelamegham | Zendy

Open Access

Glycosphingolipids on Human Myeloid Cells Stabilize E-Selectin–Dependent Rolling in the Multistep Leukocyte Adhesion Cascade

Author(s) -

Nandini Mondal,

Gino Stolfa,

Aristotelis Antonopoulos,

Yuqi Zhu,

Shuen-Shiuan Wang,

Alexander Buffone,

G. Ekin AtillaGokcumen,

Stuart M. Haslam,

Anne Dell,

Sriram Neelamegham

Publication year - 2016

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.306748

Subject(s) - ceramide , microbiology and biotechnology , cell adhesion , biology , e selectin , chemistry , cell , biochemistry , apoptosis

Recent studies suggest that the E-selectin ligands expressed on human leukocytes may differ from those in other species, particularly mice. To elaborate on this, we evaluated the impact of glycosphingolipids expressed on human myeloid cells in regulating E-selectin-mediated cell adhesion.

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