LRP1 Regulates Retinal Angiogenesis by Inhibiting PARP-1 Activity and Endothelial Cell Proliferation | Zendy

Hua Mao | Zendy; Pamela Lockyer | Zendy; W. H. Davin Townley-Tilson | Zendy; Liang Xie | Zendy; Xinchun Pi | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

LRP1 Regulates Retinal Angiogenesis by Inhibiting PARP-1 Activity and Endothelial Cell Proliferation

Author(s) -

Hua Mao,

Pamela Lockyer,

W. H. Davin Townley-Tilson,

Liang Xie,

Xinchun Pi

Publication year - 2015

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.306713

Subject(s) - lrp1 , angiogenesis , biology , microbiology and biotechnology , endothelial stem cell , cancer research , neovascularization , ldl receptor , biochemistry , lipoprotein , cholesterol , in vitro

We recently demonstrated that low-density lipoprotein receptor-related protein 1 (LRP1) is required for cardiovascular development in zebrafish. However, what role LRP1 plays in angiogenesis remains to be determined. To better understand the role of LRP1 in endothelial cell function, we investigated how LRP1 regulates mouse retinal angiogenesis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research