Basigin Promotes Cardiac Fibrosis and Failure in Response to Chronic Pressure Overload in Mice | Zendy

Kota Suzuki | Zendy; Kimio Satoh | Zendy; Shohei Ikeda | Zendy; Shinichiro Sunamura | Zendy; Tomohiro Otsuki | Zendy; Taijyu Satoh | Zendy; Nobuhiro Kikuchi | Zendy; Junichi Omura | Zendy; Ryo Kurosawa | Zendy; Masamichi Nogi | Zendy; Kazuhiko Numano | Zendy; Koichiro Sugimura | Zendy; Tatsuo Aoki | Zendy; Shunsuke Tatebe | Zendy; Satoshi Miyata | Zendy; Rupak Mukherjee | Zendy; Francis G. Spinale | Zendy; Kenji Kadomatsu | Zendy; Hiroaki Shimokawa | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Basigin Promotes Cardiac Fibrosis and Failure in Response to Chronic Pressure Overload in Mice

Author(s) -

Kota Suzuki,

Kimio Satoh,

Shohei Ikeda,

Shinichiro Sunamura,

Tomohiro Otsuki,

Taijyu Satoh,

Nobuhiro Kikuchi,

Junichi Omura,

Ryo Kurosawa,

Masamichi Nogi,

Kazuhiko Numano,

Koichiro Sugimura,

Tatsuo Aoki,

Shunsuke Tatebe,

Satoshi Miyata,

Rupak Mukherjee,

Francis G. Spinale,

Kenji Kadomatsu,

Hiroaki Shimokawa

Publication year - 2016

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.306686

Subject(s) - cardiac fibrosis , fibrosis , pressure overload , heart failure , medicine , muscle hypertrophy , basigin , endocrinology , ventricular remodeling , inflammation , matrix metalloproteinase , cardiac hypertrophy

Basigin (Bsg) is a transmembrane glycoprotein that activates matrix metalloproteinases and promotes inflammation. However, the role of Bsg in the pathogenesis of cardiac hypertrophy and failure remains to be elucidated. We examined the role of Bsg in cardiac hypertrophy and failure in mice and humans.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research