Lipoprotein-Associated Phospholipase A 2 and Incident Peripheral Arterial Disease in Older Adults | Zendy

Parveen K. Garg | Zendy; Alice M. Arnold | Zendy; Karen Hinckley Stukovsky | Zendy; Carol E. Koro | Zendy; Nancy S. Jenny | Zendy; Kenneth J. Mukamal | Zendy; Michael H. Criqui | Zendy; Curt D. Furberg | Zendy; Anne B. Newman | Zendy; Mary Cushman | Zendy

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Lipoprotein-Associated Phospholipase A ₂ and Incident Peripheral Arterial Disease in Older Adults

Author(s) -

Parveen K. Garg,

Alice M. Arnold,

Karen Hinckley Stukovsky,

Carol E. Koro,

Nancy S. Jenny,

Kenneth J. Mukamal,

Michael H. Criqui,

Curt D. Furberg,

Anne B. Newman,

Mary Cushman

Publication year - 2016

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.306647

Subject(s) - medicine , hazard ratio , confidence interval , odds ratio , lipoprotein associated phospholipase a2 , claudication , body mass index , prospective cohort study , population , cardiology , arterial disease , vascular disease , cholesterol , lipoprotein , environmental health

Although prior studies report a relationship between elevated lipoprotein-associated phospholipase A2 (Lp-PLA2) and incident cardiovascular disease, the prospective association of Lp-PLA2 with incident peripheral arterial disease (PAD) has not been studied. We investigated the association between Lp-PLA2 mass and activity and the risk of developing clinical PAD and low ankle-brachial index (ABI).

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