Deletion of Periostin Protects Against Atherosclerosis in Mice by Altering Inflammation and Extracellular Matrix Remodeling | Zendy

Jennifer A. Schwanekamp | Zendy; Angela Lorts | Zendy; Ronald J. Vagnozzi | Zendy; Davy Vanhoutte | Zendy; Jeffery D. Molkentin | Zendy

Open Access

Deletion of Periostin Protects Against Atherosclerosis in Mice by Altering Inflammation and Extracellular Matrix Remodeling

Author(s) -

Jennifer A. Schwanekamp,

Angela Lorts,

Ronald J. Vagnozzi,

Davy Vanhoutte,

Jeffery D. Molkentin

Publication year - 2015

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.306397

Subject(s) - periostin , extracellular matrix , matricellular protein , inflammation , apolipoprotein e , microbiology and biotechnology , biology , matrix metalloproteinase , endocrinology , medicine , chemistry , immunology , disease

Periostin is a secreted protein that can alter extracellular matrix remodeling in response to tissue injury. However, the functional role of periostin in the development of atherosclerotic plaques has yet to be described despite its observed induction in diseased vessels and presence in the serum.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research