Niacin Therapy Increases High-Density Lipoprotein Particles and Total Cholesterol Efflux Capacity But Not ABCA1-Specific Cholesterol Efflux in Statin-Treated Subjects
Author(s) -
Graziella E. Ronsein,
Patrick M. Hutchins,
Daniel Isquith,
Tomáš Vaisar,
Xue-Qiao Zhao,
Jay W. Heinecke
Publication year - 2015
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.115.306268
Subject(s) - niacin , efflux , abca1 , cholesterol , medicine , statin , lipoprotein , endocrinology , high density lipoprotein , chemistry , biochemistry , transporter , gene
We investigated relationships between statin and niacin/statin combination therapy and the concentration of high-density lipoprotein particles (HDL-P) and cholesterol efflux capacity, 2 HDL metrics that might better assess cardiovascular disease risk than HDL-cholesterol (HDL-C) levels.
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