Vitamin D Protects Against Atherosclerosis via Regulation of Cholesterol Efflux and Macrophage Polarization in Hypercholesterolemic Swine
Author(s) -
Kai Yin,
Yong You,
Vicki J. Swier,
Lin Tang,
Mohamed M. Radwan,
Amit N. Pandya,
Devendra K. Agrawal
Publication year - 2015
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.115.306132
Subject(s) - cholesterol , endocrinology , liver x receptor , abca1 , medicine , biology , foam cell , reverse cholesterol transport , cyp27a1 , efflux , lipoprotein , chemistry , transporter , biochemistry , nuclear receptor , transcription factor , gene
Prevalence of vitamin D (VD) deficiency and its association with the risk of cardiovascular disease prompted us to evaluate the effect of VD status on lipid metabolism and atherosclerosis in hypercholesterolemic microswine.
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