Near-Infrared Spectroscopy Enhances Intravascular Ultrasound Assessment of Vulnerable Coronary Plaque
Author(s) -
Rishi Puri,
Ryan D. Madder,
Sean Madden,
Stephen T. Sum,
Kathy Wolski,
James E. Muller,
Jordan Andrews,
Karilane L. King,
Yu Kataoka,
Kiyoko Uno,
Samir Kapadia,
E. Murat Tuzcu,
Steven E. Nissen,
Renu Virmani,
Akiko Maehara,
Gary S. Mintz,
Stephen J. Nicholls
Publication year - 2015
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.115.306118
Subject(s) - intravascular ultrasound , medicine , cardiology , ex vivo , coronary atherosclerosis , fibrous cap , vulnerable plaque , pathological , atheroma , coronary artery disease , in vivo , radiology , microbiology and biotechnology , biology
Pathological studies demonstrate the dual significance of plaque burden (PB) and lipid composition for mediating coronary plaque vulnerability. We evaluated relationships between intravascular ultrasound (IVUS)-derived PB and arterial remodeling with near-infrared spectroscopy (NIRS)-derived lipid content in ex vivo and in vivo human coronary arteries.
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