Altered Maturation Status and Possible Immune Exhaustion of CD8 T Lymphocytes in the Peripheral Blood of Patients Presenting With Acute Coronary Syndromes | Zendy

David A. Zidar | Zendy; Joseph C. Mudd | Zendy; Steven Juchnowski | Zendy; João Pedro Lopes | Zendy; Sara D. Sparks | Zendy; Samantha S. Park | Zendy; Masakazu Ishikawa | Zendy; Robyn Osborne | Zendy; Jeffrey B. Washam | Zendy; Cliburn Chan | Zendy; Nicholas Funderburg | Zendy; Adeyinka Owoyele | Zendy; Mohamad Amer Alaiti | Zendy; Myttle Mayuga | Zendy; Carl E. Orringer | Zendy; Marco A. Costa | Zendy; Daniel I. Simon | Zendy; Curtis Tatsuoka | Zendy; Robert M. Califf | Zendy; L. Kristin Newby | Zendy; Michael M. Lederman | Zendy; Kent J. Weinhold | Zendy

Open Access

Altered Maturation Status and Possible Immune Exhaustion of CD8 T Lymphocytes in the Peripheral Blood of Patients Presenting With Acute Coronary Syndromes

Author(s) -

David A. Zidar,

Joseph C. Mudd,

Steven Juchnowski,

João Pedro Lopes,

Sara D. Sparks,

Samantha S. Park,

Masakazu Ishikawa,

Robyn Osborne,

Jeffrey B. Washam,

Cliburn Chan,

Nicholas Funderburg,

Adeyinka Owoyele,

Mohamad Amer Alaiti,

Myttle Mayuga,

Carl E. Orringer,

Marco A. Costa,

Daniel I. Simon,

Curtis Tatsuoka,

Robert M. Califf,

L. Kristin Newby,

Michael M. Lederman,

Kent J. Weinhold

Publication year - 2015

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.306112

Subject(s) - peripheral blood , immune system , peripheral , cd8 , immune status , medicine , immunology , lymphocyte subsets

Inflammation in response to oxidized lipoproteins is thought to play a key role in acute coronary syndromes (ACS), but the pattern of immune activation has not been fully characterized. We sought to perform detailed phenotypic and functional analysis of CD8 T lymphocytes from patients presenting with ACS to determine activation patterns and potential immunologic correlates of ACS.

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