Fibroblast Growth Factor 23 Is Associated With Carotid Plaque Presence and Area | Zendy

Nirav Shah | Zendy; Chuanhui Dong | Zendy; Mitchell S.V. Elkind | Zendy; Ralph L. Sacco | Zendy; Armando J. Mendez | Zendy; Barry I. Hudson | Zendy; Shonni J. Silverberg | Zendy; Myles Wolf | Zendy; Tatjana Rundek | Zendy; Clinton B. Wright | Zendy

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Fibroblast Growth Factor 23 Is Associated With Carotid Plaque Presence and Area

Author(s) -

Nirav Shah,

Chuanhui Dong,

Mitchell S.V. Elkind,

Ralph L. Sacco,

Armando J. Mendez,

Barry I. Hudson,

Shonni J. Silverberg,

Myles Wolf,

Tatjana Rundek,

Clinton B. Wright

Publication year - 2015

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.305945

Subject(s) - confidence interval , odds ratio , medicine , fibroblast growth factor 23 , risk factor , population , stroke (engine) , kidney disease , logistic regression , cardiology , gastroenterology , endocrinology , surgery , parathyroid hormone , mechanical engineering , environmental health , engineering , calcium

Elevated fibroblast growth factor 23 (FGF23), a hormone that regulates phosphate homeostasis, has been associated with mortality, cardiovascular events, and stroke, and to arterial calcification in chronic kidney disease, but its role in atherosclerosis is unclear and population-based studies are lacking. We hypothesized that elevated FGF23 would associate with carotid plaque presence, area, and echogenicity in the race/ethnically diverse community-based Northern Manhattan Study (NOMAS) sample.

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