Proangiogenic Properties of Thrombospondin-4 | Zendy

Santoshi Muppala | Zendy; Ella Frolova | Zendy; Roy Xiao | Zendy; Irene Krukovets | Zendy; Suzy Yoon | Zendy; George Hoppe | Zendy; Amit Vasanji | Zendy; Edward F. Plow | Zendy; Olga SteninaAdognravi | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Proangiogenic Properties of Thrombospondin-4

Author(s) -

Santoshi Muppala,

Ella Frolova,

Roy Xiao,

Irene Krukovets,

Suzy Yoon,

George Hoppe,

Amit Vasanji,

Edward F. Plow,

Olga SteninaAdognravi

Publication year - 2015

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.305912

Subject(s) - thrombospondin , thrombospondin 1 , angiogenesis , computer science , chemistry , medicine , cancer research , biochemistry , metalloproteinase , matrix metalloproteinase

Thrombospondin-4 (TSP-4) is 1 of the 5 members of the thrombospondin protein family. TSP-1 and TSP-2 are potent antiangiogenic proteins. However, angiogenic properties of the 3 other TSPs, which do not contain the domains associated with the antiangiogeneic activity of TSP-1 and TSP-2, have not been explored. In our previous studies, we found that TSP-4 is expressed in the vascular matrix of blood vessels of various sizes and is especially abundant in capillaries. We sought to identify the function of TSP-4 in the regulation of angiogenesis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research