Exercise Promotes Collateral Artery Growth Mediated by Monocytic Nitric Oxide
Author(s) -
Stephan H. Schirmer,
Dominic Millenaar,
Christian Werner,
Lisa Schuh,
Achim Degen,
Stephanie Bettink,
Peter Lipp,
Nico van Rooijen,
Tim Meyer,
Michael Böhm,
Ulrich Laufs
Publication year - 2015
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.115.305806
Subject(s) - arteriogenesis , medicine , collateral circulation , nitric oxide , nitric oxide synthase , perfusion , femoral artery , artery , cardiology , ischemia , endocrinology
Collateral artery growth (arteriogenesis) is an important adaptive response to hampered arterial perfusion. It is unknown whether preventive physical exercise before limb ischemia can improve arteriogenesis and modulate mononuclear cell function. This study aimed at investigating the effects of endurance exercise before arterial occlusion on MNC function and collateral artery growth.
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