Implications of α v β 3 Integrin Signaling in the Regulation of Ca 2+ Waves and Myogenic Tone in Cerebral Arteries | Zendy

Rania E. Mufti | Zendy; Anil Zechariah | Zendy; María Sancho | Zendy; Neil Mazumdar | Zendy; Suzanne E. Brett | Zendy; Donald G. Welsh | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Implications of α _v β ₃ Integrin Signaling in the Regulation of Ca ²⁺ Waves and Myogenic Tone in Cerebral Arteries

Author(s) -

Rania E. Mufti,

Anil Zechariah,

María Sancho,

Neil Mazumdar,

Suzanne E. Brett,

Donald G. Welsh

Publication year - 2015

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.305619

Subject(s) - phospholipase c , myogenic contraction , phosphorylation , myosin light chain phosphatase , microbiology and biotechnology , myosin light chain kinase , signal transduction , integrin , biology , protein kinase c , chemistry , medicine , endocrinology , receptor , biochemistry , smooth muscle

The myogenic response is central to blood flow regulation in the brain. Its induction is tied to elevated cytosolic [Ca(2+)], a response primarily driven by voltage-gated Ca(2+) channels and secondarily by Ca(2+) wave production. Although the signaling events leading to the former are well studied, those driving Ca(2+) waves remain uncertain.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research