Epigenetic Regulation of Angiogenesis by JARID1B-Induced Repression of HOXA5
Author(s) -
Christian Fork,
Lunda Gu,
Juliane Hitzel,
Ivana Josipovic,
Jiong Hu,
Michael SzeKa Wong,
Yuliya Ponomareva,
Mareike Albert,
Sandra U. Schmitz,
Shizuka Uchida,
Ingrid Fleming,
Kristian Helin,
Dieter Steinhilber,
Matthias S. Leisegang,
Ralf P. Brandes
Publication year - 2015
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.115.305561
Subject(s) - psychological repression , angiogenesis , epigenetics , biology , microbiology and biotechnology , cancer research , genetics , gene , gene expression
Altering endothelial biology through epigenetic modifiers is an attractive novel concept, which is, however, just in its beginnings. We therefore set out to identify chromatin modifiers important for endothelial gene expression and contributing to angiogenesis.
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