Skin Autofluorescence as a Measure of Advanced Glycation End Products Deposition Predicts 5-Year Amputation in Patients With Peripheral Artery Disease | Zendy

Lisanne C. de Vos | Zendy; Jeltje Boersema | Zendy; Douwe J. Mulder | Zendy; Andries J. Smit | Zendy; Clark J. Zeebregts | Zendy; Joop D. Lefrandt | Zendy

Open Access

Skin Autofluorescence as a Measure of Advanced Glycation End Products Deposition Predicts 5-Year Amputation in Patients With Peripheral Artery Disease

Author(s) -

Lisanne C. de Vos,

Jeltje Boersema,

Douwe J. Mulder,

Andries J. Smit,

Clark J. Zeebregts,

Joop D. Lefrandt

Publication year - 2015

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.305407

Subject(s) - medicine , amputation , hazard ratio , peripheral , critical limb ischemia , diabetes mellitus , proportional hazards model , coronary artery disease , glycation , cardiology , area under the curve , ischemia , vascular disease , confidence interval , surgery , arterial disease , endocrinology

Patients with peripheral artery disease are at risk for critical limb ischemia and amputation. Accumulation of advanced glycation end products is increased and predictive for coronary and cerebrovascular events in several high cardiovascular risk groups. We hypothesized that accumulation of tissue advanced glycation end products, measured by skin autofluorescence (SAF), predicts amputation in patients with peripheral artery disease.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research