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Vascular Smooth Muscle Cells Are Responsible for a Prothrombotic Phenotype of Spontaneously Hypertensive Rat Arteries
Author(s) -
Karima AitAissa,
Jérémy Lagrange,
Amel Mohamadi,
Huguette Louis,
Bénédicte Houppert,
Pascal Challande,
Denis Wahl,
Patrick Lacolley,
Véronique Regnault
Publication year - 2015
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.115.305377
Subject(s) - vascular smooth muscle , phenotype , medicine , vascular disease , cardiology , blood vessel , smooth muscle , anatomy , endocrinology , pathology , biology , gene , biochemistry
The hypothesis that hypertension induces a hypercoagulable state arises from the complications associated with hypertension: stroke and myocardial infarction. Here, we determine whether hypertension causes changes in the thrombin-generating capacity of the vascular wall.

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