Resolvin E1 (RvE1) Attenuates Atherosclerotic Plaque Formation in Diet and Inflammation-Induced Atherogenesis | Zendy

Hatice Hastürk | Zendy; Rima Abdallah | Zendy; Alpdoğan Kantarcı | Zendy; Daniel Nguyen | Zendy; Nicholas Giordano | Zendy; James A. Hamilton | Zendy; Thomas E. Van Dyke | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Resolvin E1 (RvE1) Attenuates Atherosclerotic Plaque Formation in Diet and Inflammation-Induced Atherogenesis

Author(s) -

Hatice Hastürk,

Rima Abdallah,

Alpdoğan Kantarcı,

Daniel Nguyen,

Nicholas Giordano,

James A. Hamilton,

Thomas E. Van Dyke

Publication year - 2015

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.115.305324

Subject(s) - periodontitis , inflammation , medicine , porphyromonas gingivalis , systemic inflammation , gingivitis , c reactive protein , gastroenterology , pathology , immunology , dentistry

Epidemiological and recent clinical studies implicate periodontitis as an independent risk factor for cardiovascular disease. Previously, we demonstrated that rabbits with experimental periodontitis and cholesterol diet exhibit more aortic plaque compared with diet alone. We also showed that a proresolution mediator, Resolvin E1 (RvE1), reverses the experimental periodontitis. Here, we determined whether oral/topical application of RvE1 attenuates aortic atherosclerosis induced by both diet and periodontal inflammation.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research