Impairment of Wound Healing in Patients With Type 2 Diabetes Mellitus Influences Circulating MicroRNA Patterns via Inflammatory Cytokines
Author(s) -
Seema Dangwal,
Bernd Stratmann,
Claudia Bang,
Johan M. Lorenzen,
Regalla Kumarswamy,
Jan Fiedler,
Christine S. Falk,
Claus Jürgen Scholz,
Thomas Thum,
Diethelm Tschoepe
Publication year - 2015
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.114.305048
Subject(s) - medicine , type 2 diabetes mellitus , wound healing , inflammation , microrna , proinflammatory cytokine , diabetes mellitus , cytokine , immunology , endocrinology , biology , gene , biochemistry
MicroRNAs (miRNA/miR) are stably present in body fluids and are increasingly explored as disease biomarkers. Here, we investigated influence of impaired wound healing on the plasma miRNA signature and their functional importance in patients with type 2 diabetes mellitus.
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