Epigenetic Profile of Human Adventitial Progenitor Cells Correlates With Therapeutic Outcomes in a Mouse Model of Limb Ischemia
Author(s) -
Miriam Gubernator,
Sadie C. Slater,
Helen Spencer,
Inmaculada Spiteri,
Andrea Sottoriva,
Federica Riu,
Jonathan Rowlinson,
Elisa Avolio,
Rajesh Katare,
Giuseppe Mangialardi,
Atsuhiko Oikawa,
Carlotta Reni,
Paola Campagnolo,
Gaia Spinetti,
Anestis Touloumis,
Simon Tavaré,
Francesca Romana Prandi,
Maurizio Pesce,
Manuela Hofner,
Klemens Vierlinger,
Costanza Emanueli,
Gianni D. Angelini,
Paolo Madeddu
Publication year - 2015
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.114.304989
Subject(s) - epigenetics , dna methylation , progenitor cell , biology , transplantation , cancer research , microbiology and biotechnology , umbilical vein , gene silencing , immunology , medicine , stem cell , gene , in vitro , gene expression , genetics
We investigated the association between the functional, epigenetic, and expressional profile of human adventitial progenitor cells (APCs) and therapeutic activity in a model of limb ischemia.
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