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Possible Involvement of Minor Lysophospholipids in the Increase in Plasma Lysophosphatidic Acid in Acute Coronary Syndrome
Author(s) -
Makoto Kurano,
Akiko Suzuki,
Asuka Inoue,
Yasunori Tokuhara,
Kuniyuki Kano,
Hirotaka Matsumoto,
Koji Igarashi,
Ryunosuke Ohkawa,
Kazuhiro Nakamura,
Tomotaka Dohi,
Katsumi Miyauchi,
Hiroyuki Daida,
Kazuhisa Tsukamoto,
Hitoshi Ikeda,
Junken Aoki,
Yutaka Yatomi
Publication year - 2014
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.114.304748
Subject(s) - lysophosphatidic acid , acute coronary syndrome , cardiology , inflammation , medicine , chemistry , myocardial infarction , receptor
Lysophosphatidic acids (LPA) have important roles in the field of vascular biology and are derived mainly from lysophosphatidylcholine via autotaxin. However, in our previous study, only the plasma LPA levels, and not the serum autotaxin levels, increased in patients with acute coronary syndrome (ACS). The aim of this study was to elucidate the pathway by which LPA is increased in patients with ACS.

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