Protein Tyrosine Phosphatase 1B Impairs Diabetic Wound Healing Through Vascular Endothelial Growth Factor Receptor 2 Dephosphorylation | Zendy

Jing Zhang | Zendy; Limin Li | Zendy; Jing Li | Zendy; Yuan Liu | Zendy; ChenYu Zhang | Zendy; Yujing Zhang | Zendy; Ke Zen | Zendy

Open Access

Protein Tyrosine Phosphatase 1B Impairs Diabetic Wound Healing Through Vascular Endothelial Growth Factor Receptor 2 Dephosphorylation

Author(s) -

Jing Zhang,

Limin Li,

Jing Li,

Yuan Liu,

ChenYu Zhang,

Yujing Zhang,

Ke Zen

Publication year - 2014

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.114.304705

Subject(s) - dephosphorylation , protein tyrosine phosphatase , wound healing , vascular endothelial growth factor , medicine , growth factor , receptor , phosphatase , endocrinology , phosphorylation , microbiology and biotechnology , cancer research , chemistry , biology , vegf receptors , immunology

Impaired wound healing is a major complication of diabetes mellitus. The mechanisms that govern wound healing, however, are complex and incompletely understood. In the present study, we determined the inhibitory role of protein tyrosine phosphatase 1B (PTP1B) in the process of diabetic wound healing.

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