Metabolic Syndrome Individuals With and Without Type 2 Diabetes Mellitus Present Generalized Vascular Dysfunction | Zendy

Guillaume Walther | Zendy; Philippe Obert | Zendy; Frédéric Dutheil | Zendy; Robert Chapier | Zendy; Bruno Lesourd | Zendy; Géraldine Naughton | Zendy; Daniel Courteix | Zendy; Agnès Vinet | Zendy

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Metabolic Syndrome Individuals With and Without Type 2 Diabetes Mellitus Present Generalized Vascular Dysfunction

Author(s) -

Guillaume Walther,

Philippe Obert,

Frédéric Dutheil,

Robert Chapier,

Bruno Lesourd,

Géraldine Naughton,

Daniel Courteix,

Agnès Vinet

Publication year - 2015

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.114.304591

Subject(s) - medicine , endothelial dysfunction , microcirculation , metabolic syndrome , type 2 diabetes , abdominal obesity , endocrinology , type 2 diabetes mellitus , diabetes mellitus , cardiology , microangiopathy , sodium nitroprusside , vasodilation , nitric oxide

The first objective of this study was to demonstrate differences within endothelial-dependent and endothelial-independent vasoreactivity in macro- and microcirculation beds among patients with metabolic syndrome (MetS) with and without type 2 diabetes mellitus (T2D) compared with healthy counterparts. The second objective was to determine relationships among the function of macro- and microvascular systems and abdominal adiposity, as well as inflammatory markers in the 3 groups.

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