Coronary Endothelial Dysfunction Is Associated With Inflammation and Vasa Vasorum Proliferation in Patients With Early Atherosclerosis | Zendy

ByoungJoo Choi | Zendy; Yoshiki Matsuo | Zendy; Tatsuo Aoki | Zendy; TaekGeun Kwon | Zendy; Abhiram Prasad | Zendy; Rajiv Gulati | Zendy; Ryan J. Len | Zendy; Lilach O. Lerman | Zendy; Amir Lerman | Zendy

Open Access

Coronary Endothelial Dysfunction Is Associated With Inflammation and Vasa Vasorum Proliferation in Patients With Early Atherosclerosis

Author(s) -

ByoungJoo Choi,

Yoshiki Matsuo,

Tatsuo Aoki,

TaekGeun Kwon,

Abhiram Prasad,

Rajiv Gulati,

Ryan J. Len,

Lilach O. Lerman,

Amir Lerman

Publication year - 2014

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.114.304445

Subject(s) - vasa vasorum , endothelial dysfunction , optical coherence tomography , medicine , coronary atherosclerosis , cardiology , inflammation , coronary artery disease , coronary arteries , artery , endothelium , radiology

Endothelial dysfunction is an early manifestation of atherosclerosis. Inflammation and vasa vasorum play a pivotal role in the pathophysiology of plaque initiation, development, and complications. Optical coherence tomography allows high-resolution imaging of tissue microstructure. Therefore, the aim of this study was to test the hypothesis that segments with endothelial dysfunction show macrophages and vasa vasorum in patients with early coronary artery disease.

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