Platelets Are Highly Activated in Patients of Chronic Thromboembolic Pulmonary Hypertension
Author(s) -
Nobuhiro Yaoita,
Ryutaro Shirakawa,
Yoshihiro Fukumoto,
Koichiro Sugimura,
Satoshi Miyata,
Yutaka Miura,
Kotaro Nochioka,
Masanobu Miura,
Shunsuke Tatebe,
Tatsuo Aoki,
Saori Yamamoto,
Kimio Satoh,
Tomohiro Kimura,
Hiroaki Shimokawa,
Hisanori Horiuchi
Publication year - 2014
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.114.304404
Subject(s) - platelet , interquartile range , rhoa , medicine , thrombus , pulmonary hypertension , platelet activation , cardiology , gastroenterology , thrombin , pulmonary artery , chemistry , biochemistry , signal transduction
Chronic thromboembolic pulmonary hypertension (CTEPH) is a fatal disease that is distinct from pulmonary arterial hypertension (PAH). Although CTEPH is characterized by obstruction of major pulmonary artery because of chronic thrombus, it remains unclear whether CTEPH is associated with prothrombotic condition.
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