Vascular Endothelial Growth Factor Overexpression Does Not Enhance Adipose Stromal Cell–Induced Protection on Muscle Damage in Critical Limb Ischemia | Zendy

Fernanda D. Olea | Zendy; Paola Locatelli | Zendy; Anna P. Hnatiuk | Zendy; Andrea De Lorenzi | Zendy; León Valdivieso | Zendy; Estefanía Rocha | Zendy; Rodrigo RamírezCampillo | Zendy; R Laguens | Zendy; Alberto Crottogini | Zendy

Open Access

Vascular Endothelial Growth Factor Overexpression Does Not Enhance Adipose Stromal Cell–Induced Protection on Muscle Damage in Critical Limb Ischemia

Author(s) -

Fernanda D. Olea,

Paola Locatelli,

Anna P. Hnatiuk,

Andrea De Lorenzi,

León Valdivieso,

Estefanía Rocha,

Rodrigo RamírezCampillo,

R Laguens,

Alberto Crottogini

Publication year - 2014

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.114.304348

Subject(s) - stromal cell , critical limb ischemia , adipose tissue , ischemia , medicine , vascular endothelial growth factor , muscle damage , cardiology , vegf receptors , vascular disease , arterial disease

Critical limb ischemia complicates peripheral artery disease leading to tissue damage and amputation. We hypothesized that modifying adipose stromal cells (ASCs) to overexpress human vascular endothelial growth factor 165 (VEGF) would limit ischemic muscle damage to a larger extent than nonmodified ASCs.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research