Nucleoside Diphosphate Kinase B Regulates Angiogenesis Through Modulation of Vascular Endothelial Growth Factor Receptor Type 2 and Endothelial Adherens Junction Proteins | Zendy

Yuxi Feng | Zendy; Shalini Gross | Zendy; Nadine M. Wolf | Zendy; Vicki M. Butenschön | Zendy; Yi Hua Qiu | Zendy; Kavi Devraj | Zendy; Stefan Liebner | Zendy; Jens Krøll | Zendy; Edward Y. Skolnik | Zendy; HansPeter Hammes | Zendy; Thomas Wieland | Zendy

Open Access

Nucleoside Diphosphate Kinase B Regulates Angiogenesis Through Modulation of Vascular Endothelial Growth Factor Receptor Type 2 and Endothelial Adherens Junction Proteins

Author(s) -

Yuxi Feng,

Shalini Gross,

Nadine M. Wolf,

Vicki M. Butenschön,

Yi Hua Qiu,

Kavi Devraj,

Stefan Liebner,

Jens Krøll,

Edward Y. Skolnik,

HansPeter Hammes,

Thomas Wieland

Publication year - 2014

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.114.304239

Subject(s) - angiogenesis , adherens junction , microbiology and biotechnology , vascular endothelial growth factor , biology , kinase insert domain receptor , vascular endothelial growth factor a , human umbilical vein endothelial cell , s1pr1 , umbilical vein , chemistry , cancer research , biochemistry , cadherin , in vitro , cell , vegf receptors

Nucleoside diphosphate kinase B (NDPKB) participates in the activation of heterotrimeric and monomeric G proteins, which are pivotal mediators in angiogenic signaling. The role of NDPKB in angiogenesis has to date not been defined. Therefore, we analyzed the contribution of NDPKB to angiogenesis and its underlying mechanisms in well-characterized in vivo and in vitro models.

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