Lower Apo A-I and Lower HDL-C Levels Are Associated With Higher Intermediate CD14 ++ CD16 + Monocyte Counts That Predict Cardiovascular Events in Chronic Kidney Disease | Zendy

Kyrill S. Rogacev | Zendy; Adam M. Zawada | Zendy; Insa E. Emrich | Zendy; Sarah Seiler | Zendy; Michael Böhm | Zendy; Danilo Fliser | Zendy; Kevin Woollard | Zendy; Gunnar H. Heine | Zendy

Open Access

Lower Apo A-I and Lower HDL-C Levels Are Associated With Higher Intermediate CD14 ⁺⁺ CD16 ⁺ Monocyte Counts That Predict Cardiovascular Events in Chronic Kidney Disease

Author(s) -

Kyrill S. Rogacev,

Adam M. Zawada,

Insa E. Emrich,

Sarah Seiler,

Michael Böhm,

Danilo Fliser,

Kevin Woollard,

Gunnar H. Heine

Publication year - 2014

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.114.304172

Subject(s) - cd14 , cholesterol , cd36 , monocyte , endocrinology , medicine , lipoprotein , abca1 , cd68 , apolipoprotein b , kidney disease , cd16 , apolipoprotein e , biology , immunology , biochemistry , immune system , receptor , immunohistochemistry , cd3 , disease , transporter , gene , cd8

Patients with chronic kidney disease (CKD) display impaired cholesterol efflux capacity and elevated CD14(++)CD16(+) monocyte counts. In mice, dysfunctional cholesterol efflux causes monocytosis. It is unknown whether cholesterol efflux capacity and monocyte subsets are associated in CKD.

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