Open AccessEstrogen Effects on Vascular Inflammation Are Age Dependent
Author(s) -
Meaghan Bowling,
Dongqi Xing,
Akash Kapadia,
Yiu-Fai Chen,
Alexander J. Szalai,
Suzanne Oparil,
Fadi G. Hage
Publication year - 2014
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.114.303629
Subject(s) - estrogen , inflammation , medicine , endocrinology
17β-Estradiol (E2) offers cardiovascular protection in young female animals and postmenopausal women. In contrast, randomized trials of menopausal hormones performed in older women have shown harm or no cardiovascular benefit. We hypothesize that E2 effects on vascular inflammation are age dependent.
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