The H2.0-Like Homeobox Transcription Factor Modulates Yolk Sac Vascular Remodeling in Mouse Embryos
Author(s) -
Claudia Prahst,
Bahar Kasaai,
Filipa Moraes,
Espen D. Jahnsen,
Bruno Larrivée,
David Villegas,
Luc Pardanaud,
Laurence Pibouin-Fragner,
Feng Zhang,
Hans C. Zaun,
Anne Eichmann,
Elizabeth A. V. Jones
Publication year - 2014
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.114.303626
Subject(s) - homeobox , homeobox a1 , dlx5 , microbiology and biotechnology , transcription factor , hnf1b , yolk sac , homeobox protein nkx 2.5 , biology , embryo , cdx2 , emx2 , anatomy , gene , genetics
The H2.0-like homeobox transcription factor (HLX) plays an essential role in visceral organogenesis in mice and has been shown to regulate angiogenic sprouting in vitro and in zebrafish embryos. We therefore examined the role of HLX in vascular development in mouse and avian embryos.
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