Impact of Phospholipid Transfer Protein on Nascent High-Density Lipoprotein Formation and Remodeling | Zendy

Ailing Ji | Zendy; Joanne M. Wroblewski | Zendy; Nancy R. Webb | Zendy; Deneys R. van der Westhuyzen | Zendy

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Impact of Phospholipid Transfer Protein on Nascent High-Density Lipoprotein Formation and Remodeling

Author(s) -

Ailing Ji,

Joanne M. Wroblewski,

Nancy R. Webb,

Deneys R. van der Westhuyzen

Publication year - 2014

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.114.303533

Subject(s) - phospholipid transfer protein , lipid anchored protein , apolipoprotein b , phospholipid , abca1 , chemistry , lipoprotein , efflux , cholesterol , reverse cholesterol transport , biochemistry , microbiology and biotechnology , transporter , high density lipoprotein , biology , membrane , autophagy , gene , apoptosis

Phospholipid transfer protein (PLTP), which binds phospholipids and facilitates their transfer between lipoproteins in plasma, plays a key role in lipoprotein remodeling, but its influence on nascent high-density lipoprotein (HDL) formation is not known. The effect of PLTP overexpression on apolipoprotein A-I (apoA-I) lipidation by primary mouse hepatocytes was investigated.

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