Disabled-2 Is Required for Efficient Hemostasis and Platelet Activation by Thrombin in Mice | Zendy

Hui-Ju Tsai | Zendy; ChienLing Huang | Zendy; YaoWen Chang | Zendy; Ding-Yuan Huang | Zendy; Chung-Ching Lin | Zendy; Jonathan A. Cooper | Zendy; Ju-Chien Cheng | Zendy; ChingPing Tseng | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Disabled-2 Is Required for Efficient Hemostasis and Platelet Activation by Thrombin in Mice

Author(s) -

Hui-Ju Tsai,

ChienLing Huang,

YaoWen Chang,

Ding-Yuan Huang,

Chung-Ching Lin,

Jonathan A. Cooper,

Ju-Chien Cheng,

ChingPing Tseng

Publication year - 2014

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.114.302602

Subject(s) - platelet , thrombin , platelet activation , hemostasis , microbiology and biotechnology , clot retraction , chemistry , megakaryocyte , biology , immunology , medicine , stem cell , haematopoiesis

The essential role of platelet activation in hemostasis and thrombotic diseases focuses attention on unveiling the underlying intracellular signals of platelet activation. Disabled-2 (Dab2) has been implicated in platelet aggregation and in the control of clotting responses. However, there is not yet any in vivo study to provide direct evidence for the role of Dab2 in hemostasis and platelet activation.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research