Platelet Glycoprotein Ib-IX as a Regulator of Systemic Inflammation | Zendy

Adam Corken | Zendy; Susan Russell | Zendy; Judith Dent | Zendy; Steven R. Post | Zendy; Jerry Ware | Zendy

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Platelet Glycoprotein Ib-IX as a Regulator of Systemic Inflammation

Author(s) -

Adam Corken,

Susan Russell,

Judith Dent,

Steven R. Post,

Jerry Ware

Publication year - 2014

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.113.303113

Subject(s) - regulator , glycoprotein , platelet , inflammation , platelet membrane glycoprotein , glycoprotein ib , immunology , chemistry , microbiology and biotechnology , medicine , biology , biochemistry , gene

The platelet glycoprotein Ib-IX (GP Ib-IX) receptor is a well-characterized adhesion receptor supporting hemostasis and thrombosis via interactions with von Willebrand factor. We examine the GP Ib-IX/von Willebrand factor axis in murine polymicrobial sepsis, as modeled by cecal ligation and puncture (CLP).

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